cees dekker Things To Know Before You Buy
cees dekker Things To Know Before You Buy
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2009, discovery of a whole new phenotype for microorganisms in slim nanofluidic slits; and initially detection of neighborhood protein constructions along DNA making use of reliable-condition nanopores
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Deposition and atomic drive microscopy of unique phthalocyanine polymers concerning nanofabricated electrodes
We create point-of-treatment diagnostics examination of neglected tropical ailments within useful resource-constrained settings, based on Crspr/Cas9 detecting of pathogen’s DNA in system fluids.
The coiled-coil in the human Rad50 DNA repair protein incorporates certain segments of elevated adaptability
Because 2000 he moved to single-molecule biophysics and nanobiology, with investigate from DNA supercoiling scientific tests of nucleosomes and DNA mend proteins to DNA translocation by means of nanopores. Lately his research has centered on learning mobile division with micro organism on chip, even though his final interest is from the direction of realizing artificial cells.
Atomic force microscopy displays that vaccinia topoisomerase IB generates filaments on DNA in a very cooperative fashion
In 1993, being a youthful and eager associate professor at Delft University of Know-how, I'd initially targeted the exploration endeavours of my group on measuring the electrical conductance of just one conducting-polymer molecule. cees dekker In two decades, we had developed a device where only one wire of a phthalocyaninepolysiloxane polymer was connected among two carefully spaced steel nanoelectrodes.
Resolving the step size in condensin-driven DNA loop extrusion identifies ATP binding given that the move-producing system
An integrated microfluidic System for quantifying drug permeation throughout biomimetic vesicle membranes
Numerous new phenomena were being uncovered, and he and his study team proven a leading situation Within this industry of analysis. Dekker and his research group discovered new physics of nanotubes and also explored the feasibility of molecular electronics. In 1998, they were the 1st to build a transistor based upon just one nanotube molecule.
One example is, we consider the nucleopore complicated, a gateway between the mobile nucleus as well as the cytoplasm. This is a very sophisticated process and so tough to study inside of a cell, so we use biomimetics. We reconstruct holes and after that insert unique aspects from the nucleopore elaborate to review transport by way of it at the single-molecule stage.’
It had been an exceedingly intriguing time, through which I received plenty of guidance from Delft College of Technologies, the place I had been a professor at some time, and I started out many collaborations with molecular biologists. That served me learn a whole lot.’